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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK3
All Species:
15.45
Human Site:
S354
Identified Species:
34
UniProt:
P51956
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51956
NP_001139571.1
506
57705
S354
S
V
H
L
R
K
A
S
S
P
N
L
H
R
R
Chimpanzee
Pan troglodytes
XP_001160306
495
56653
S343
S
V
H
L
R
K
A
S
S
P
N
L
H
R
R
Rhesus Macaque
Macaca mulatta
XP_001106955
504
57509
S352
S
V
H
L
R
K
A
S
S
P
N
L
H
R
R
Dog
Lupus familis
XP_543184
1286
146207
S706
R
S
V
I
S
V
T
S
A
L
K
E
V
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A5
511
57204
T353
R
Q
E
H
G
S
H
T
S
P
A
S
P
H
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513217
507
57493
N354
I
S
H
P
R
R
E
N
S
P
S
P
H
R
R
Chicken
Gallus gallus
XP_001232686
498
56944
D352
E
V
L
S
G
I
T
D
L
T
H
L
R
R
R
Frog
Xenopus laevis
Q7ZZC8
944
104521
T552
K
L
G
L
N
Q
Y
T
A
G
I
I
N
H
E
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
V444
D
V
T
Q
P
K
I
V
E
A
L
L
G
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
V371
V
R
A
S
A
S
P
V
R
P
R
Q
P
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
S560
F
S
T
V
T
T
R
S
R
P
S
L
N
S
Q
Conservation
Percent
Protein Identity:
100
96.8
95.4
22.4
N.A.
72.9
N.A.
N.A.
74.5
62.2
21.2
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.2
96.8
31.6
N.A.
82.9
N.A.
N.A.
86.3
76.4
34.2
40.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
20
N.A.
N.A.
46.6
26.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
26.6
N.A.
N.A.
66.6
33.3
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
23
Protein Similarity:
N.A.
N.A.
N.A.
47.5
N.A.
37.5
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
28
0
19
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
10
0
10
0
0
10
0
0
19
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
19
0
0
0
0
10
0
0
10
10
0
% G
% His:
0
0
37
10
0
0
10
0
0
0
10
0
37
19
0
% H
% Ile:
10
0
0
10
0
10
10
0
0
0
10
10
0
0
0
% I
% Lys:
10
0
0
0
0
37
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
10
37
0
0
0
0
10
10
10
55
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
28
0
19
0
0
% N
% Pro:
0
0
0
10
10
0
10
0
0
64
0
10
19
0
0
% P
% Gln:
0
10
0
10
0
10
0
0
0
0
0
10
0
0
10
% Q
% Arg:
19
10
0
0
37
10
10
0
19
0
10
0
10
55
55
% R
% Ser:
28
28
0
19
10
19
0
46
46
0
19
10
0
10
10
% S
% Thr:
0
0
19
0
10
10
19
19
0
10
0
0
0
0
0
% T
% Val:
10
46
10
10
0
10
0
19
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _